Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI9D10), TrueMAB
Human ESRRA 단백질(aa 1-205)을 항원으로 한 Mouse IgG1 단클론 항체. Western blot에 최적화(1:2,000 희석). Lyophilized 형태, PBS buffer(8% trehalose) 보존. 연구용으로 사용하며, 지방산 대사 관련 ERRα 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–205 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan nuclear hormone receptor.
ERR family members share an almost identical DNA-binding domain with 68% identity to the estrogen receptor.
This protein binds to an ERRα response element (ERRE) containing a consensus half-site (5′-tnaaggtca-3′) and may regulate the MCAD promoter.
ERR1 functions as a metabolic regulator and is expressed in tissues that preferentially metabolize fatty acids.
The corresponding gene is NR3B1.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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