Thermo Fisher Scientific Neurensin 2 Polyclonal Antibody
Neurensin 2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human 시료 반응성이 있으며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며, -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NRSN2 (Accession Q9GZP1), corresponding to amino acid residues E167–S204 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853291 |
Product Specific Information
This antibody detects endogenous levels of total NRSN2.
Target Information
Neurensin-2 (NRSN2) is a 204 amino acid multi-pass membrane protein belonging to the VMP family, possibly involved in vesicle transport and maintenance. It is expressed in the brain, localizing to the hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus. NRSN2 is considered a potential tumor suppressor gene and a candidate biomarker for long-term survival in hepatocellular carcinoma (HCC).
The gene encoding Neurensin-2 maps to human chromosome 20, which contains approximately 63 million bases and over 600 genes. Some of these genes are associated with neurological and genetic disorders such as Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome, and Alagille syndrome. Chromosome 20 also includes regions thought to be important for seminal production and potential targets for male contraception.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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