Thermo Fisher Scientific Complement C5 Polyclonal Antibody
Thermo Fisher Scientific의 Complement C5 Polyclonal Antibody는 인간 C5 단백질을 인식하는 sheep polyclonal 항체로, IHC(P)와 면역확산(IEF)에 사용됩니다. 비결합형 액상 형태로 제공되며, 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | |
| Immunodiffusion (IDF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human C5, purified from plasma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2550585 |
Target Information
The protein encoded by this gene is the fifth component of complement (C5), which plays a critical role in inflammatory and cell killing processes.
This protein consists of alpha and beta polypeptide chains linked by a disulfide bridge.
Upon activation, the C5a peptide—an anaphylatoxin with potent spasmogenic and chemotactic activity—is generated from the alpha chain.
The C5b fragment forms a complex with C6, initiating the formation of the membrane attack complex (MAC).
Mutations in this gene can lead to complement component 5 deficiency, resulting in increased susceptibility to severe infections.
Defects in this gene have also been associated with liver fibrosis and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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