Thermo Fisher Scientific LDLR Recombinant Rabbit Monoclonal Antibody (10K4L8)
LDLR 단백질을 인식하는 토끼 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 HEK293 세포에서 발현된 재조합 항체입니다. 고순도 액상 제형으로 안정적인 신호 검출이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10K4L8 |
| Immunogen | Synthetic peptide within amino acids 761–860 of human LDL Receptor (LDLR) (NP_000518.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094196 |
Product Specific Information
Immunogen sequence:
TVEIVTMSHQ ALGDVAGRGN EKKPSSVRAL SIVLPIVLLV FLCLGVFLLW KNWRLKNINS INFDNPVYQK TTEDEVHICH NQDGYSYPSR QMVSLEDDVA
Target Information
The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL binds at the cell membrane and is internalized, leading to cholesterol release and regulation of HMG CoA reductase activity. Mutations in the LDL-R gene cause familial hypercholesterolemia. LDL-R also serves as an entry factor for Hepatitis C virus along with SCARB1, CLDN1, and CD81. At least three isoforms of LDL-R are known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-51226_LDLR_P01130-1_Rabbit.svg / MA5-51226_LDLR_P01130-1_Rabbit_PDP.jpeg)
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