Thermo Fisher Scientific SARS-CoV-2 Spike (N501Y Mutant) Recombinant Rabbit Monoclonal Antibody (1J5G2)
SARS-CoV-2 Spike 단백질(N501Y 변이)에 특이적인 재조합 토끼 단클론 항체. Western blot 및 ELISA 검증 완료. HEK293 세포 발현, 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1J5G2 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 450–550 of coronavirus SARS-CoV-2 Spike RBD (N501Y) (YP_009724390.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3090490 |
Product Specific Information
Immunogen sequence:
NYLYRLFRKS NLKPFERDIS TEIYQAGSTP CNGVEGFNCY FPLQSYGFQP TYGVGYQPYR VVVLSFELLH APATVCGPKK STNLVKNKCV NFNFNGLTGT G
Target Information
The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection.
SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion.
The S protein undergoes two crucial cleavage events, with the first splitting S1 and S2 and the second splitting S2 into FP and S2’ [PMID: 33466921].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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