Thermo Fisher Scientific SUR1 Polyclonal Antibody
Thermo Fisher Scientific의 SUR1 Polyclonal Antibody는 인간 ABCC8 단백질을 인식하는 토끼 IgG 항체로, IHC 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: -
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal (aa 1567–1581) of human ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636288 |
Product Specific Information
This antibody detects endogenous levels of total ABCC8 protein.
Target Information
The gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies. This protein belongs to the MRP subfamily, involved in multidrug resistance. It modulates ATP-sensitive potassium channels and insulin release. Mutations can lead to hyperinsulinemic hypoglycemia of infancy or non-insulin-dependent diabetes mellitus type II. Alternative splicing variants have been observed but not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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