Thermo Fisher Scientific ALX4 Monoclonal Antibody (KAB4)

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

The ALX4 gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue.
Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones.
It is also associated with frontonasal dysplasia featuring alopecia and hypogonadism, indicating a role in craniofacial development and hair follicle formation.
Deletion of chromosome segment 11(p11p12) containing this gene causes Potocki-Shaffer syndrome (PSS), characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males.
In mice, this gene uses dual translation initiation sites located 16 codons apart.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.