Thermo Fisher Scientific TNFRSF14/HVEM Polyclonal Antibody
Human TNFRSF14/HVEM 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. KLH-conjugated synthetic peptide로부터 유래하며, Protein A로 정제된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human TNFRSF14 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and acts as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV glycoprotein D (gD) to TNFRSF14 is part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 interacts with TRAF family members, mediating signal transduction pathways that activate immune responses. Activation in T cells promotes proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants have been described, though not all full-length forms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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