Thermo Fisher Scientific Glucose-6-Phosphate Dehydrogenase Polyclonal Antibody, HRP

Thermo Fisher Scientific Glucose-6-Phosphate Dehydrogenase Polyclonal Antibody, HRP

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot and freeze at -20°C or below.
• Avoid freeze/thaw cycles.
• Centrifuge if not clear after standing at room temperature.
• Stable for several weeks at 4°C as undiluted liquid.
• Dilute only prior to immediate use.

Glucose-6-Phosphate Dehydrogenase antibody is an IgG fraction purified from monospecific antiserum via delipidation, salt fractionation, and ion exchange chromatography, followed by extensive dialysis.
Immunoelectrophoresis shows a single precipitin arc against anti-Peroxidase, anti-Goat Serum, and purified Glucose-6-Phosphate-Dehydrogenase [Yeast].
Cross-reactivity with other tissues or species may occur but is not specifically determined.

Target Information

Glucose-6-Phosphate Dehydrogenase (G6PD) is a cytosolic enzyme encoded by an X-linked housekeeping gene.
It produces NADPH, essential for defense against oxidative stress and reductive biosynthetic reactions.
G6PD exhibits high genetic diversity; many variants arise from missense mutations with differing enzyme activity and clinical outcomes.
Deficiency may lead to neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia.
Two transcript variants encoding distinct isoforms are known.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.