Thermo Fisher Scientific Aldolase A Polyclonal Antibody
Thermo Fisher Scientific의 Aldolase A Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 토끼 유래 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 고순도의 Affinity Chromatography 정제 항체로, 세포질 내 Aldolase A 단백질 검출에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–348 of human ALDOA (NP_9089301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804672 |
Product Specific Information
Immunogen sequence:
MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HIYLEGTLLK PNMVTPGHAC TQKFSHEEIA MATVTALRRT VPPAVTGITF LSGGQSEEEA SINLNAINKC PLLKPWALTF SYGRALQASA LKAWGGKKEN LKAAQEEYVK RALANSLACQ GKYTPSGQ
Positive Samples: MCF7, DU145, 293T, HepG2, Jurkat, A-549, CEM, Mouse skeletal muscle, Mouse kidney
Cellular Location: Cytoplasm, I band, M line, myofibril, sarcomere
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. This glycolytic enzyme catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.
Three aldolase isozymes (A, B, and C), encoded by separate genes, are differentially expressed during development. Mutations in this gene are associated with Glycogen Storage Disease XII, an autosomal recessive disorder related to hemolytic anemia. Disruption of this gene also contributes to the progression of multiple cancer types. Related pseudogenes are found on chromosomes 3 and 10.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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