Thermo Fisher Scientific RAC2 Polyclonal Antibody
RAC2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 1.81 mg/mL 농도, PBS/glycerol buffer 보존. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–192 of human RAC2 (NP_0028631) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804668 |
Product Specific Information
- Positive Samples: HL-60
- Cellular Location: Cytoplasm
- Immunogen Sequence:
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRACS LL
Target Information
RAC, a small GTPase in the ras family, regulates membrane ruffle, lamellipodia, and filopodia formation. It is involved in actin cytoskeletal organization and cellular transformation. P21 activated kinases (PAKs) are direct targets of active Rac and Cdc42, inducing polarized cytoskeletal structures in fibroblasts. RAC1 and RAC2 are essential components of NADPH oxidase, responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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