Thermo Fisher Scientific RALBP1 Polyclonal Antibody
RALBP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ELISA에 적합하며, 높은 특이성과 재현성을 제공. 액상 형태로 공급되며, -20°C에서 보관. 연구용으로만 사용 가능.
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- PA588123
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 396–655 of human RALBP1 (NP_0067791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804670 |
Product Specific Information
Immunogen Sequence:
AGIKEEIRRQ EFLLNCLHRD LQGGIKDLSK EERLWEVQRI LTALKRKLRE AKRQECETKI AQEIASLSKE DVSKEEMNEN EEVINILLAQ ENEILTEQEE LLAMEQFLRR QIASEKEEIE RLRAEIAEIQ SRQQHGRSET EEYSSESESE SEDEEELQII LEDLQRQNEE LEIKNNHLNQ AIHEEREAII ELRVQLRLLQ MQRAKAEQQA QEDEEPEWRG GAVQPPRDGV LEPKAAKEQP KAGKEPAKPS PSRDRKETSIPositive Samples: A-673, Mouse spleen, Mouse lung
Cellular Location: Membrane, Peripheral membrane protein
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42 but not RALA.
It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), serving as the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
RALBP1 also catalyzes transport of glutathione conjugates and xenobiotics, contributing to multidrug resistance.
Acts as a scaffold protein, assembling proteins for endocytotic complex formation during interphase and interacting with CDC2 to regulate endocytosis.
One of its substrates includes EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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