Thermo Fisher Scientific RALBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 396-655 of human RALBP1 (NP_0067791) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RALBP1,uniProtId:Q15311-1,ncbiNodeId:9606,antigenRange:396-655,antigenLength:655,antigenImageFileName:PA5-88123_RALBP1_Q15311-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88123_RALBP1_Q15311-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

8.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804670

Product Specific Information

Immunogen sequence: AGIKEEIRRQ EFLLNCLHRD LQGGIKDLSK EERLWEVQRI LTALKRKLRE AKRQECETKI AQEIASLSKE DVSKEEMNEN EEVINILLAQ ENEILTEQEE LLAMEQFLRR QIASEKEEIE RLRAEIAEIQ SRQQHGRSET EEYSSESESE SEDEEELQII LEDLQRQNEE LEIKNNHLNQ AIHEEREAII ELRVQLRLLQ MQRAKAEQQA QEDEEPEWRG GAVQPPRDGV LEPKAAKEQP KAGKEPAKPS PSRDRKETSI; Positive Samples: A-673, Mouse spleen, Mouse lung; Cellular Location: Membrane, Peripheral membrane protein

Target Information

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.