ELK Biotechnology ATX7 rabbit pAb
상품 옵션 정보 | ||||||
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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
ES9411-100UL | ELK Biotechnology ES9411-100UL ATX7 rabbit pAb, 100UL pk | 재고문의 | pk | 469,000원 | 515,900원 | |
ES9411-50UL | ELK Biotechnology ES9411-50UL ATX7 rabbit pAb, 50UL pk | 재고문의 | pk | 320,000원 | 352,000원 |
다른 상품 둘러보기
Product name: | ATX7 rabbit pAb |
Applications: | WB;ELISA |
Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 260-340 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 98kD |
GeneID(Human): | 6314 |
Human Swiss-Prot No: | O15265 |
Cellular localization: | [Isoform a]: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.; [Isoform b]: Cytoplasm. |
Background: | ataxin 7(ATXN7) Homo sapiens The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the pure cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmi |
Species Reactivity: | Human;Mouse |
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