Thermo Fisher Scientific WRN Polyclonal Antibody
WRN 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 적합합니다. 인간 Werner Syndrome Helicase의 400–450번 잔기 영역을 면역원으로 사용하며, 1 mg/mL 농도의 액상 형태로 제공됩니다.
- 카탈로그번호
- A300238Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific WRN Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 400 and 450 of Human Werner Syndrome Helicase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair.
This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses intrinsic 3′ to 5′ DNA helicase activity and also a 3′ to 5′ exonuclease activity.
Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, it may be involved in the repair of double-strand DNA breaks.
Defects in this gene cause Werner syndrome, an autosomal recessive disorder characterized by premature aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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