Thermo Fisher Scientific GTF2IRD1 Polyclonal Antibody
GTF2IRD1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC에 적합합니다. C-말단 합성 펩타이드로부터 유래되었으며, PBS와 sucrose buffer에 보관됩니다. 단백질 A 정제, 1 mg/mL 농도, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human GTF2IRD1 (aa 873–922) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576695 |
Product Specific Information
Peptide sequence:
VIINQLQPFA EICNDAKVPA KDSSIPKRKR KRVSEGNSVS SSSSSSSSSS
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Yeast: 79%
Target Information
Williams-Beuren syndrome (WBS) is a developmental disorder caused by a hemizygous microdeletion on chromosome 7q11.23. It is an autosomal dominant condition characterized by physical, cognitive, and behavioral traits such as facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies, and neurologic abnormalities.
The WBSCR11 gene, also known as GTF2IRD1, GRF2IRD1, GTF3, Cream1, and MusTRD1, is located within the WBS deletion region and encodes a transcription factor potentially contributing to developmental symptoms in WBS. It is expressed in all adult tissues as several variants, showing discrete spatial and temporal expression during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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