Thermo Fisher Scientific SCP2 Recombinant Rabbit Monoclonal Antibody (JE62-79)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The transcript from the proximal promoter encodes the longer SCPx protein, and the transcript from the distal promoter encodes the shorter SCP2 protein, with both sharing a common C-terminus.
SCPx functions as a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, while SCP2 acts as an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, where cells are deficient in peroxisomes and have impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.