Thermo Fisher Scientific SCP2 Recombinant Rabbit Monoclonal Antibody (JE62-79)
SCP2 단백질을 인식하는 토끼 유래 재조합 단일클론 항체로, Western blot과 IHC(Paraffin)에 최적화됨. HEK293 세포에서 발현된 IgG 형식의 항체이며, Protein A로 정제됨. 인간 및 생쥐 시료에 반응하며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE62-79 |
| Immunogen | Synthetic peptide within human Sterol carrier protein 2 aa 14–64/547 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931278 |
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The transcript from the proximal promoter encodes the longer SCPx protein, and the transcript from the distal promoter encodes the shorter SCP2 protein, with both sharing a common C-terminus.
SCPx functions as a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, while SCP2 acts as an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, where cells are deficient in peroxisomes and have impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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