Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (BL-205-2G8)
SMC1 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로, Western blot, IHC, ICC, Flow cytometry, IP 등에 사용 가능. Human 및 Mouse 반응성. HEK293F 발현, 1 mg/mL 농도의 액상형, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BL-205-2G8 |
| Immunogen | Synthetic peptide representing a region between residue 1200 and the C-terminus (residue 1233) of Human structural maintenance of chromosomes 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These proteins are conserved in eukaryotes and are essential for proper mitotic chromosome segregation. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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