Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (BL-205-2G8)
Thermo Fisher Scientific의 SMC1 재조합 토끼 단클론 항체(BL-205-2G8)는 Human과 Mouse에 반응하며, 다양한 면역실험(WB, IHC, ICC, Flow, IP)에 사용 가능. HEK293 세포에서 발현된 고순도 항체로, 4°C에서 보관하며 연구용으로 적합.
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Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (BL-205-2G8)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1 µL per 1 × 10⁶ cells |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BL-205-2G8 |
| Immunogen | Synthetic peptide representing a region between residue 1200 and the C-terminus (residue 1233) of human structural maintenance of chromosomes 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note:
- For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events requiring structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex essential for metaphase progression and sister chromatid cohesion. Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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