Thermo Fisher Scientific CNTNAP2 Polyclonal Antibody
CNTNAP2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 신경계 발달 및 관련 질환 연구에 활용됩니다. 동결 건조 형태로 제공되며 장기 보관 시 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CNTNAP2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from extracellular domain of mouse Contactin associated protein like 2 (CNTNAP2) conjugated to an immunogenic carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CNTNAP2.
Target Information
The CNTNAP2 gene encodes a member of the neurexin family functioning in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats, laminin G domains, F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains, and a putative PDZ binding site.
It is localized at the juxtaparanodes of myelinated axons, mediating neuron-glia interactions during nervous system development and involved in potassium channel localization within differentiating axons.
CNTNAP2 spans almost 1.5% of chromosome 7, one of the largest human genes, and is regulated by FOXP2, a transcription factor related to speech and language development.
Mutations or dysregulation of this gene have been implicated in various neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD, and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.