
Thermo Fisher Scientific LRAT Polyclonal Antibody
LRAT 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot 및 Immunocytochemistry에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 비결합형 액상 형태로 안정적인 장기 보관이 가능합니다.
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Thermo Fisher Scientific LRAT Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:100–1:2,000
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human LRAT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720770 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Lecithin retinol acyltransferase (LRAT) is a membrane-bound enzyme that catalyzes the transfer of an acyl group from the sn-1 position of lecithin to vitamin A, generating all-trans-retinyl esters (tREs) in liver, lung, and retinal pigmented epithelium.
LRAT also exchanges palmitoyl groups between RPE65 and tREs, playing a key role in the visual pathway.
It is essential for dietary mobilization, transport, and storage of vitamin A and synthesis of the visual pigment chromophore.
Loss of LRAT correlates with early-onset severe retinal dystrophy, while reduced expression may be associated with invasive bladder cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-77043_LRAT_O95237-1_Rabbit.svg, PA5-77043_LRAT_O95237-1_Rabbit_PDP.jpeg)
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