Thermo Fisher Scientific KCNH1 Polyclonal Antibody
Rabbit polyclonal antibody against human KCNH1, validated for WB. Recognizes voltage-gated potassium channel subunit involved in neuronal and muscle function. Affinity-purified with >95% purity. Supplied in PBS with glycerol, suitable for research use ...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human KCNH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720769 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Voltage-gated potassium (Kv) channels represent a complex class of voltage-gated ion channels with diverse physiological roles, including regulation of neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
KCNH1 encodes a member of the potassium channel, voltage-gated, subfamily H, which forms a pore-forming (alpha) subunit of a non-inactivating delayed rectifier potassium channel. It is activated during myoblast differentiation and is highly expressed in brain and myoblasts. Overexpression may promote tumor cell proliferation. Alternative splicing produces two distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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