Thermo Fisher Scientific PSD-95 Polyclonal Antibody
PSD-95 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며, 다양한 종(쥐, 인간, 개, 소, 마우스)에서 반응 예측. 고순도 액상 형태로 안정적이며, 연구용으로만 사용 가능.
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Thermo Fisher Scientific PSD-95 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 0.1–0.3 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EEQARKAFDRATK) corresponding to the internal amino acids of DLG4 (aa 667–680) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980383 |
Product Specific Information
- This antibody is predicted to react with bovine, canine, human, and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum.
PSD-95 contains three PDZ domains, followed by an SH3 domain and a yeast guanylate kinase homology (GuK) domain. It plays a role in clustering NMDA receptors and Shaker-type potassium channels at the synaptic membrane in CNS neurons.
Interactions occur via:
- C-terminal T/SXV motifs shared by NMDA receptors and potassium channels.
- PDZ-PDZ interactions with neuronal nitric oxide synthase (nNOS).
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
(이미지 위치: PA5-19114_PSD-95_P31016-1_Goat.svg, PA5-19114_PSD-95_P31016-1_Goat_PDP.jpeg)
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