Thermo Fisher Scientific PSD-95 Polyclonal Antibody

Thermo Fisher Scientific PSD-95 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 0.1–0.3 µg/mL
• Publications: [References not provided]

Product Specifications

Product Specific Information

• This antibody is predicted to react with bovine, canine, human, and mouse based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Target Information

Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum.
PSD-95 contains three PDZ domains, followed by an SH3 domain and a yeast guanylate kinase homology (GuK) domain. It plays a role in clustering NMDA receptors and Shaker-type potassium channels at the synaptic membrane in CNS neurons.
Interactions occur via:

1. C-terminal T/SXV motifs shared by NMDA receptors and potassium channels.
2. PDZ-PDZ interactions with neuronal nitric oxide synthase (nNOS).

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

제품 이미지

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