Thermo Fisher Scientific Caveolin 3 Polyclonal Antibody
Caveolin-3 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트에 반응하며, 근육 세포막 단백질 연구에 유용합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–6 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EHTDLEAQIVKDIH) corresponding to the N-terminus amino acids of CAV3 (aa 5–18) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982249 |
Product Specific Information
- This antibody is predicted to react with bovine, canine, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and regulates their activity. Caveolin-3 may also modulate voltage-gated potassium channels and plays a role in sarcolemma repair in skeletal muscle and cardiomyocytes. It mediates recruitment of CAVIN2 and CAVIN3 proteins to caveolae. Mutations in the CAV3 gene are associated with HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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