Thermo Fisher Scientific HCCS Polyclonal Antibody, MaxPab
HCCS 단백질을 인식하는 Thermo Fisher Scientific의 Polyclonal 항체. Western blot에 최적화되어 있으며, 인체 시료 반응성. Affinity chromatography로 정제된 액상 형태로 제공되며, 연구용으로 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HCCS (AAH01691.1, 1–268 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MGLSPSAPAV AVQASNASAS PPSGCPMHEG KMKGCPVNTE PSGPTCEKKT YSVPAHQERA YEYVECPIRG TAAENKENLD PSNLMPPPNQ TPAPDQPFAL STVREESSIP RADSEKKWVY PSEQMFWNAM LKKGWKWKDE DISQKDMYNI IRIHNQNNEQ AWKEILKWEA LHAAECPCGP SLIRFGGKAK EYSPRARIRS WMGYELPFDR HDWIINRCGT EVRYVIDYYD GGEVNKDYQF TILDVRPALD SLSAVWDRMK VAWWRWTS
Target Information
CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein belonging to the cytochrome c-type heme lyase family.
It contains two HRM (heme regulatory motif) repeats and catalyzes the covalent linkage of a heme group to the apoprotein of cytochrome c.
The HCCS gene is located on the human X chromosome. Mutations in this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS).
MCOPS7 is an X-linked male-lethal disorder associated with eye malformation, unilateral or bilateral microphthalmia, linear skin defects in females, and male embryonic lethality.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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