Thermo Fisher Scientific HCCS Monoclonal Antibody (3C7)
Thermo Fisher Scientific의 HCCS Monoclonal Antibody (3C7)는 인간 HCCS 단백질에 특이적으로 반응하는 mouse IgG2a 형 단일클론 항체입니다. ELISA 및 Immunoprecipitation에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1 ng/mL
Immunoprecipitation (IP)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C7 |
| Immunogen | Full-length recombinant HCCS (AAH01691, 1–268 a.a) protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MGLSPSAPAV AVQASNASAS PPSGCPMHEG KMKGCPVNTE PSGPTCEKKT YSVPAHQERA YEYVECPIRG TAAENKENLD PSNLMPPPNQ TPAPDQPFAL STVREESSIP RADSEKKWVY PSEQMFWNAM LKKGWKWKDE DISQKDMYNI IRIHNQNNEQ AWKEILKWEA LHAAECPCGP SLIRFGGKAK EYSPRARIRS WMGYELPFDR HDWIINRCRT EVRYVIDYYD GGEVNKDYQF TILDVRPALD SLSAVWDRMK VAWWRWTS
Target Information
CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein belonging to the cytochrome c-type heme lyase family. It contains two HRM (heme regulatory motif) repeats and facilitates the covalent linkage of a heme group to cytochrome c apoprotein.
The HCCS gene is located on the human X chromosome. Mutations in this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS). MCOPS7 is an X-linked male-lethal disorder characterized by eye deformation, microphthalmia, linear skin defects in affected females, and in utero lethality for males.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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