Thermo Fisher Scientific HCK Monoclonal Antibody (1D9-1A9)
Human HCK 단백질을 인식하는 Mouse monoclonal antibody (Clone 1D9-1A9). Western blot, ELISA, Immunoprecipitation에 적합. Affinity chromatography로 정제된 액상 형태, PBS buffer에 보존. -20°C에서 보관, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D9-1A9 |
| Immunogen | HCK (AAH14435, 1 a.a. ~ 505 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGCMKSKFLQ VGGNTSSKTE TSASPHCPVY VPDPTSTIKP GPNSHNSNTP GIREAGSEDI IVVALYDYEA IHHEDLSFQK GDQMVVLEES GEWWKARSLA TRKEGYIPSN YVARVDSLET EEWFFKGISR KDAERQLLAP GNMLGSFMIR DSETTKGSYS LSVRDYDPRQ GDTVKHYKIR TLDNGGFYIS PRSTFSTLQE LVDHYKKGND GLCQKLSVPC MSSKPQKPWE KDAWEIPRES LKLEKKLGAG QFGEVWMATY NKHTKVAVKT MKPGSMSVEA FLAEANVMKT LQHDKLVKLH AVVTKEPIYI ITEFMAKGSL LDFLKSDEGS KQPLPKLIDF SAQIAEGMAF IEQRNYIHRD LRAANILVSA SLVCKIADFG LARVIEDNEY TAREGAKFPI KWTAPEAINF GSFTIKSDVW SFGILLMEIV TYGRIPYPGV SNPEVIRALE RGYRMPRPEN CPEELYNIMM RCWKNRPEER PTFEYIQSVL DDFYTATESQ YQQQP
Target Information
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in certain forms of leukemia.
HCK (Alias: DKFZp686D0638) is a protein-tyrosine kinase predominantly expressed in hemopoietic cell types.
The encoded protein may help couple the Fc receptor to activation of the respiratory burst and may play a role in neutrophil migration and degranulation.
Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in two different isoforms with distinct subcellular localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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