Thermo Fisher Scientific RGR Polyclonal Antibody
Thermo Fisher Scientific의 RGR Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 항체입니다. 면역세포화학(ICC/IF)에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 197–218. Recombinant protein control fragment (Product #RP-109777) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092208 |
Product Specific Information
- Immunogen sequence: SLMEQKLGKS GHLQVNTTLP AR
- Antigen sequence identity: Mouse 68%; Rat 77%
Target Information
This gene encodes a putative retinal G-protein coupled receptor, a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins that bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein functions as a photoisomerase catalyzing the conversion of all-trans-retinal to 11-cis-retinal, complementing rhodopsin’s reverse isomerization in retinal photoreceptor cells. Expression is localized to tissues adjacent to retinal photoreceptor cells, including the retinal pigment epithelium and Müller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP). Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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