Thermo Fisher Scientific Human Neuroserpin Recombinant Protein, PeproTech
인체 유래 Neuroserpin 재조합 단백질로, E. coli 발현 시스템에서 생산된 44.8 kDa 비당화 단백질입니다. 세포 증식 활성 평가에 사용되며, ≥96% 순도를 보장합니다. 뇌 신경 성장 및 시냅스 가소성 연구에 적합한 연구용 단백질입니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Functional Assay
- Tested Dilution: Assay-dependent
Miscellaneous (PubMed)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Rat |
| Expression System | E. coli |
| Amino Acid Sequence | MTGATFPEEA IADLSVNMYN RLRATGEDEN ILFSPLSIAL AMGMMELGAQ GSTQKEIRHS MGYDSLKNGE EFSFLKEFSN MVTAKESQYV MKIANSLFVQ NGFHVNEEFL QMMKKYFNAA VNHVDFSQNV AVANYINKWV ENNTNNLVKD LVSPRDFDAA TYLALINAVY FKGNWKSQFR PENTRTFSFT KDDESEVQIP MMYQQGEFYY GEFSDGSNEA GGIYQVLEIP YEGDEISMML VLSRQEVPLA TLEPLVKAQL VEEWANSVKK QKVEVYLPRF TVEQEIDLKD VLKALGITEI FIKDANLTGL SDNKEIFLSK AIHKSFLEVN EEGSEAAAVS GMIAISRMAV LYPQVIVDHP FFFLIRNRRT GTILFMGRVM HPETMNTSGH DFEEL |
| Molecular Weight | 44.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 96% (by SDS-PAGE and HPLC) |
| Endotoxin Concentration | < 1 EU/µg |
| Activity | Dose-dependent stimulation of rat C6 cell proliferation (0.3–0.6 µg/ml) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human Neuroserpin is a 44.8 kDa non-glycosylated protein containing 395 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain and preferentially inhibits tissue-type plasminogen activator. It plays a role in regulating axonal growth and synaptic plasticity. Mutations in this gene cause familial encephalopathy with neuroserpin inclusion bodies (FENIB), a dominantly inherited form of encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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