Thermo Fisher Scientific PPAPDC3 Polyclonal Antibody
Thermo Fisher Scientific의 PPAPDC3 폴리클로날 항체는 인간, 마우스, 랫트 반응성을 가지며 WB 및 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 심장 조직을 양성 대조군으로 사용할 수 있습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide from near the amino terminus of human PPAPDC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C에서 3개월 보관, 장기 보관 시 –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153575 |
Product Specific Information
- Suggested positive control: mouse heart tissue lysate
- PA5-20866 can be used with blocking peptide PEP-0980
Target Information
PPAPDC3 (Phosphatidic acid phosphatase type 2 domain-containing protein 3), also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins.
It is a member of the PAP2 superfamily of phosphatases and haloperoxidases.
PPAPDC3 acts as a negative regulator of myoblast differentiation by diminishing the activity of mammalian target of rapamycin (TOR).
It is highly expressed in cardiac and skeletal muscle and is upregulated during myoblast differentiation.
Overexpression represses myogenesis, while knockdown promotes differentiation, indicating its regulatory role in myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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