Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
SLC6A8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫드 반응성이 있으며, 고순도(>95%) 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 590–635 of human SLC6A8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553888 |
Product Specific Information
- Detects endogenous SLC6A8 protein at ~70 kDa.
- Purity >95% by SDS-PAGE.
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein belonging to the sodium/neurotransporter (SNF) family.
It is expressed in kidney, skeletal muscle, heart, brain, prostate, testis, and colon.
SLC6A8 transports creatine into and out of cells, particularly in brain and muscle tissue.
Defects in SLC6A8 gene cause X-linked creatine deficiency syndrome, characterized by facial anomalies, seizures, and mental retardation.
Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-37060_SLC6A8_P48029-1_Rabbit.svg, PA5-37060_SLC6A8_P48029-1_Rabbit_PDP.jpeg)
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