Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183, Thr221) Recombinant Rabbit Monoclonal Antibody (ARC0193)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0193

Immunogen

A synthetic phosphorylated peptide around T183 of human JNK1 (P45983) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:JNK1/JNK2/JNK3,uniProtId:P45984-1,ncbiNodeId:9606,antigenRange:181-185|183,antigenLength:424,antigenImageFileName:MA5-35834_JNK1JNK2JNK3_P45984-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35834_JNK1JNK2JNK3_P45984-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:JNK1/JNK2/JNK3,uniProtId:P53779-1,ncbiNodeId:9606,antigenRange:221,antigenLength:464,antigenImageFileName:MA5-35834_JNK1JNK2JNK3_P53779-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35834_JNK1JNK2JNK3_P53779-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.61 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849734

Product Specific Information

Immunogen sequence: MMTPY

Target Information

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.