Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183, Thr221) Recombinant Rabbit Monoclonal Antibody (ARC0193)
Phospho-JNK1/JNK2/JNK3 (Thr183, Thr221) 인산화 부위를 인식하는 재조합 토끼 단클론 항체. Western blot, IHC, ICC, ELISA에 적합. 인간, 마우스, 랫트 시료 반응. 고순도의 Affinity Chromatography 정제. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0193 |
| Immunogen | A synthetic phosphorylated peptide around T183 of human JNK1 (P45983) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849734 |
Product Specific Information
Immunogen sequence: MMTPY
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. These kinases are serine-threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus. JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals, and JNK is expressed as ten different isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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