Thermo Fisher Scientific HMBS Polyclonal Antibody
HMBS 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human HMBS recombinant protein (Position: N6–H361) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2746488 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
PBGD (porphobilinogen deaminase), also known as hydroxymethylbilane synthase (HMBS), is a cytoplasmic enzyme involved in the heme biosynthesis pathway. Deficiency of PBGD causes errors in pyrrole metabolism, leading to the inherited disorder acute intermittent porphyria (AIP).
AIP is characterized by acute neurological dysfunctions such as hypertension, tachycardia, peripheral neuropathy, abdominal pain, and increased urinary aminolevulinic acid and porphobilinogen levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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