Thermo Fisher Scientific CCDC22 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CCDC22. Recombinant protein control fragment (Product #RP-91924). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC22,uniProtId:O60826-1,ncbiNodeId:9606,antigenRange:86-204,antigenLength:627,antigenImageFileName:PA5-51477_CCDC22_O60826-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51477_CCDC22_O60826-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639440

Product Specific Information

Immunogen sequence: YQNFLYPSEP DLRDLLLFLA ERLPTDASED ADQPAGDSAI LLRAIGSQIR DQLALPWVPP HLRTPKLQHL QGSALQKPFH ASRLVVPELS SRGEPREFQA SPLLLPVPTQ VPQPVGRVA

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.

Target Information

CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.