Thermo Fisher Scientific CCDC22 Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal Anti-CCDC22 항체로 Western blot, IHC, ICC/IF에 적합. Recombinant CCDC22 단백질을 면역원으로 사용. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 안정적인 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CCDC22. Recombinant protein control fragment (Product #RP-91924). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639440 |
Product Specific Information
Immunogen sequence:
YQNFLYPSEP DLRDLLLFLA ERLPTDASED ADQPAGDSAI LLRAIGSQIR DQLALPWVPP HLRTPKLQHL QGSALQKPFH ASRLVVPELS SRGEPREFQA SPLLLPVPTQ VPQPVGRVA
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 87%
Target Information
CCDC22 is a recently identified coiled-coil domain-containing protein that binds copines, which are calcium-dependent, membrane-binding proteins involved in calcium signaling.
In rat, CCDC22 localizes to multiple brain regions including the prefrontal and somatosensory cortex, dentate gyrus, thalamus, and spinal cord motor neurons after sciatic nerve transection, suggesting a role in neuronal injury response.
The human CCDC22 gene is a novel candidate gene for syndromic X-linked intellectual disability (XLID).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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