Thermo Fisher Scientific DGCR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DGCR2. Recombinant protein control fragment (Product #RP-91328).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640544

Product Specific Information

Immunogen sequence: RFSRKCPTGW HHYEGTASCY RVYLSGENYW DAAQTCQRLN GSLATFSTDQ ELRFVLAQEW DQPERSFGWK DQRKLWVGYQ YVITGRNRSL EGRWEVAFKG SSEVFLPPDP IFASAMSEND NVFCAQLQCF HFPTLRHHDL HSWHAESCYE KSSFLCKRSQ TCVDIKDNVV DEGFYFTPK

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.