Thermo Fisher Scientific AHA1 Polyclonal Antibody
AHA1 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 및 -20°C 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Reference |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AHA1. Recombinant protein control fragment (Product #RP-88922). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637779 |
Product Specific Information
Immunogen sequence:
PTMNGESVDP VGQPALKTEE RKAKPAPSKT QARPVGVKIP TCKITLKETF LTSPEELYRV FTTQELVQAF THAPATLEAD RGGKFHMVDG NVSGEFTDLV PEKHIVMKWR FKSWPEGHFA TITLTFIDKN GETELCMEGR GIPAPEEE
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1, increasing its chaperone activity. Competes with inhibitory co-chaperones FNIP1 and TSC1 for binding to HSP90AA1, providing a reciprocal regulatory mechanism for chaperoning of client proteins. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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