Thermo Fisher Scientific TWIST1 Monoclonal Antibody (2F8E7)
TWIST1 단백질을 인식하는 Mouse Monoclonal Antibody(2F8E7)로, Human 시료에 반응합니다. Western blot, ELISA, ICC/IF 등 다양한 응용에 적합하며, 고순도 Protein G 정제 및 안정적인 액상 형태로 제공됩니다.
- 카탈로그번호
- MA517195
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TWIST1 Monoclonal Antibody (2F8E7)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200 | View publication |
| ELISA | 1:10,000 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F8E7 |
| Immunogen | Purified recombinant fragment of human TWIST1 (amino acids 9–74) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538666 |
Product Specific Information
MA5-17195 targets TWIST1 in indirect ELISA and WB applications, showing reactivity with Human samples.
The immunogen is a purified recombinant fragment of human TWIST1 (amino acids 9–74) expressed in E. coli.
MA5-17195 detects TWIST1, which has a predicted molecular weight of approximately 21 kDa.
Target Information
TWIST1 acts as a transcriptional regulator. It inhibits myogenesis by sequestering E proteins, suppresses trans-activation by MEF2, and blocks DNA-binding by MYOD1 through physical interaction.
TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B, and regulates cranial suture patterning and fusion. Mutations in TWIST1 are implicated in Saethre-Chotzen syndrome, characterized by coronal synostosis, brachycephaly, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.