Thermo Fisher Scientific TIS11D Polyclonal Antibody
TIS11D 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 WB 및 IHC(P) 검증 완료. 1 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–250 of human TIS11D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553439 |
Product Specific Information
This antibody detects endogenous TIS11D protein at a molecular weight of approximately 40 kDa.
Purity is >95% by SDS-PAGE.
Target Information
TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2, or RNF162C, is a 494 amino acid protein localized in the nucleus and containing two CSH1-type zinc fingers.
It belongs to the TIS11 family of early response proteins and functions as a nuclear transcription factor that binds to 5′UUAUUUAUUU-3′ RNA sequences, potentially regulating growth factor-induced cellular responses.
The TIS11D gene is located on human chromosome 2, which contains over 1,400 genes and constitutes nearly 8% of the human genome.
Mutations in related genes such as ABCA12, ABCG5, and ABCG8 are associated with disorders including harlequin ichthyosis and sitosterolemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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