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Thermo Fisher Scientific DGKE Polyclonal Antibody
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DGKE 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC(P) 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%)이며 4°C 또는 -20°C에서 보관 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 26. 오전 07:00
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Thermo Fisher Scientific PA536250 DGKE Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
630,500원VAT 포함 693,550원
Thermo Fisher Scientific · Thermo Fisher Scientific DGKE Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 180–230 of human DGK-epsilon |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553440 |
Product Specific Information
- Detects endogenous DGKE protein at a molecular weight of approximately 64 kDa.
- Purity >95% as determined by SDS-PAGE.
Target Information
Diacylglycerol (DAG) functions as an intracellular activator of protein kinase C (PKC) and guanine nucleotide exchange factors, influencing various cell signaling pathways. To maintain cellular homeostasis, DAG levels are regulated by diacylglycerol kinases (DGKs), which phosphorylate DAG to phosphatidic acid.
- Type I DGKs (DGK-α, -β, -γ): Contain calcium-binding EF-hand motifs.
- Type II DGKs (DGK-δ, DGK-ι): Contain N-terminal pleckstrin homology (PH) domains.
- Type III DGK-ε: Contains no identifiable regulatory domains (64 kDa).
- Type IV DGKs (DGK-ζ, DGK-ι): Contain C-terminal ankyrin repeats.
- Type V DGK-θ: Contains three cysteine-rich domains and a PH domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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