Thermo Fisher Scientific hnRNP H2 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Detects endogenous hnRNP H2 protein at a molecular weight of approximately 50 kDa.
• Purity is greater than 95% as determined by SDS-PAGE.

Target Information

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three quasi-RRM domains that bind to RNAs and is highly similar to HNRPH1.
This gene is implicated in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein.
[Information provided by RefSeq]

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.