Thermo Fisher Scientific hnRNP H2 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로 hnRNP H2 단백질 검출에 사용. Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 보장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA536254
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 180–230 of human hnRNP H2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553441 |
Product Specific Information
- Detects endogenous hnRNP H2 protein at a molecular weight of approximately 50 kDa.
- Purity is greater than 95% as determined by SDS-PAGE.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three quasi-RRM domains that bind to RNAs and is highly similar to HNRPH1.
This gene is implicated in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein.
[Information provided by RefSeq]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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