Thermo Fisher Scientific SMN1/SMN2 Monoclonal Antibody (2B1)
SMN1/SMN2 단백질 검출용 마우스 단일클론 항체. Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용 가능. 42kDa 밴드 검출. Protein A 정제, PBS 버퍼 및 sodium azide 포함. 연구용 전용.
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Thermo Fisher Scientific SMN1/SMN2 Monoclonal Antibody (2B1)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent | |
| Flow Cytometry (Flow) | Assay-dependent | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent | 1 publication available |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Xenopus |
| Published Species | Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B1 |
| Immunogen | Purified recombinant His₆-tagged SMN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087364 |
Product Specific Information
MA1-5878 detects SMN in human, mouse, and xenopus samples.
It has been successfully used in Western blot, immunoprecipitation, immunofluorescence, immunohistochemistry (paraffin), flow cytometry, and ELISA procedures.
MA1-5878 detects a band of approximately 42 kDa.
The immunogen is purified recombinant His₆-tagged SMN protein (human).
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13.
This duplicated region contains at least four genes and repetitive elements, making it prone to rearrangements and deletions.
The telomeric and centromeric copies of this gene are nearly identical and encode the same protein — survival motor neuron (SMN) protein.
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins, essential components of the spliceosome.
Mutations in the SMN1 gene cause spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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