Thermo Fisher Scientific DOK2 Polyclonal Antibody
DOK2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 분석에 적합. Human, Mouse, Rat 시료에 반응하며, 친화 크로마토그래피로 정제됨. PBS, 50% 글리세롤 및 0.02% 아지드 포함. -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK2 (Accession O60496), corresponding to amino acid residues R273–Q323 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818431 |
Product Specific Information
This antibody detects endogenous levels of total DOK2.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for the p210(bcr/abl) chimeric protein, whose presence is associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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