
Thermo Fisher Scientific RORB Monoclonal Antibody (OTI4B7), TrueMAB
인간 RORB 단백질(아미노산 1-260)을 항원으로 한 Mouse IgG1 단클론 항체. Western blot에서 1:2,000 희석으로 검증됨. 무보존제, 동결건조 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human RORB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Retinoid-related orphan receptor beta (RORβ) is a nuclear receptor (NR1 family) involved in central nervous system development, sensory input integration, and circadian rhythm regulation.
Disruption of RORβ in mice leads to juvenile ataxia, retinal degeneration, abnormal circadian activity, and delayed male fertility.
RORβ binds monomeric response elements containing the sequence AnnTAGGTCA.
An alternatively spliced isoform, RORβ2, is expressed mainly in the pineal gland and retina.
RORβ expression has been observed in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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