Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI2D7), TrueMAB
인간 MMP3 단백질(아미노산 246-477)에 특이적인 단클론 항체. Western blot에 최적화된 TrueMAB 포맷으로 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며, PBS 완충액(8% 트레할로스) 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin‑1) belongs to the peptidase M10A subfamily. It is secreted as a pro‑protein and activated by extracellular protease cleavage. The active enzyme binds zinc and calcium ions and exhibits metallo‑endopeptidase activity, degrading collagen, gelatin, fibronectin, and laminin. MMP3 is involved in wound repair and tissue remodeling; mutations in its gene are associated with coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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