Thermo Fisher Scientific CD243 (ABCB1) Monoclonal Antibody (UIC2)
CD243 (ABCB1) 단백질을 인식하는 UIC2 클론의 mouse monoclonal antibody. 인간 시료 반응성으로 IHC, Flow Cytometry, IP, Functional Assay 등에 사용 가능. 1 mg/mL 농도의 액상 형태로, preservative-free PBS buffer에 보관. 4°C에서 보관, 동결 금지.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific CD243 (ABCB1) Monoclonal Antibody (UIC2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| Immunoprecipitation (IP) | Assay-Dependent |
| Functional Assay (Functional) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UIC2 |
| Immunogen | Human CD243 (MDR-1) cDNA-transfected NIH 3T3 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745546 |
Product Specific Information
This antibody recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, and on many multidrug-resistant cancer cells.
It preferentially recognizes CD243 during substrate transport.
Low endotoxin, azide-free phosphate-buffered saline (PBS) solution, 0.2 µm filter sterilized.
Endotoxin level is less than 0.01 EU/µg of protein (LAL test).
Recommended Application Notes:
- Immunohistochemistry (Paraffin): Heat-mediated antigen retrieval in citrate buffer (pH 6)
- Functional Application: Inhibition
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily.
ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
CD243 (P-glycoprotein) is a member of the MDR/TAP subfamily and functions as an ATP-dependent drug efflux pump with broad substrate specificity.
It contributes to multidrug resistance by decreasing drug accumulation in cells and mediates resistance to anticancer drugs.
Additionally, it acts as a transporter in the blood-brain barrier.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 없음 또는 제거됨)
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD45 Monoclonal Antibody (MEM-55), Alexa Fluor 700
529,900원
Thermo Fisher Scientific
Thermo Fisher Scientific CD87 (UPAR) Monoclonal Antibody (VIM5), PE
441,900원
Thermo Fisher Scientific
Thermo Fisher Scientific CD243 (ABCB1) Monoclonal Antibody (UIC2)
261,000원
Thermo Fisher Scientific
Thermo Fisher Scientific CD140a (PDGFRA) Monoclonal Antibody (16A1), FITC
362,700원
Thermo Fisher Scientific
Thermo Fisher Scientific CD203c Monoclonal Antibody (NP4D6), FITC
354,900원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|