Thermo Fisher Scientific Lactotransferrin/Lactoferrin/LTF Monoclonal Antibody (LTF/4073)
인간 Lactotransferrin(Lactoferrin/LTF)을 인식하는 Mouse IgG2a 단클론 항체입니다. IHC, ICC, Flow Cytometry 등 다양한 면역분석에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 단백질 A/G 정제, PBS 용액 형태로 보존.
- 카탈로그번호
- 4057-MSM3-P1ABX
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LTF/4073 |
| Immunogen | Recombinant fragment (around aa614–645) of human Lactotransferrin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). It is found in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules. LF plays roles in iron homeostasis, microbial defense, anti-inflammatory responses, cellular growth regulation, and cancer protection. LTF acts as a first-line defense against microbial infections by binding and removing Fe³⁺ and exhibits bactericidal and proteolytic activities. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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