Thermo Fisher Scientific CaV1.3 Monoclonal Antibody (S48), APC
CaV1.3 단백질을 인식하는 마우스 단클론 항체(S48)로, APC 형광 표지되어 있습니다. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합하며, 사람·마우스·랫트 시료에서 반응합니다. 단백질 G로 정제된 액상 형태로 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S48 |
| Immunogen | Fusion protein amino acids 859–875 of rat Cav1.3 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.46 mM phosphate / 2.48 mM MES, pH 7.4, with 2 mM EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931845 |
Available Formats
- Unconjugated (MA5-27716)
- FITC (MA5-45392)
- PE (MA5-45394)
- PerCP (MA5-45393)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45391 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 250 kDa. No cross-reactivity against Cav1.2.
Target Information
CACNA1D, also known as PASNA, SANDD, or Cav1.3, encodes the alpha-1D subunit of voltage-dependent calcium channels. These channels mediate calcium ion entry into excitable cells and are involved in muscle contraction, hormone and neurotransmitter release, and gene expression. Calcium channels are composed of alpha-1, beta, alpha-2/delta, and gamma subunits, with the alpha-1 subunit forming the pore and determining channel properties. Multiple isoforms exist due to alternative splicing of the alpha-1 subunit gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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