Thermo Fisher Scientific SLC6A4 Recombinant Rabbit Monoclonal Antibody (16H2L7)
SLC6A4 단백질을 인식하는 재조합 토끼 단클론 항체로, 인간·마우스·랫트에 반응합니다. WB 및 ICC/IF에 사용 가능하며 높은 특이성과 일관성을 제공합니다. 단백질 A로 정제된 액상 항체로, 연구용 신경전달 관련 단백질 분석에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 16H2L7 |
| Immunogen | Peptides corresponding to Human SLC6A4 (aa 444–462, 16–29) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2633059 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, and Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal-origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
SERT (Serotonin Transporter) is an integral membrane protein responsible for transporting serotonin from synaptic spaces into presynaptic neurons. This process terminates serotonin activity and recycles it in a sodium-dependent manner.
SERT is a known target for psychomotor stimulants such as amphetamines and cocaine and belongs to the sodium:neurotransmitter symporter family.
Promoter polymorphisms of this gene have been linked to variations in serotonin uptake rate and may be associated with sudden infant death syndrome, aggressive behavior in Alzheimer’s disease, and depression susceptibility under emotional stress.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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