
Thermo Fisher Scientific FASN Recombinant Rabbit Monoclonal Antibody (10H14L16)
Thermo Fisher Scientific의 FASN Recombinant Rabbit Monoclonal Antibody (10H14L16)는 인간 및 마우스 FASN 단백질을 인식하는 고특이성 항체입니다. Western blot과 ICC/IF에 적합하며, 재조합 단일클론으로 로트 간 일관성과 높은 민감도를 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10H14L16 |
| Immunogen | Protein corresponding to Human FASN (aa 2200–2470) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633056 |
Product Specific Information
This antibody is predicted to react with Monkey and Galago.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
Fatty acid synthase (FASN) is a multifunctional enzyme that catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, producing long-chain saturated fatty acids. In certain cancer cell lines, FASN has been found fused with estrogen receptor-alpha (ER-alpha), where the N-terminus of FASN is fused in-frame with the C-terminus of ER-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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